A boy with growth disturbance caused by hypothalamic damage associated with intracranial hypotension syndrome following a motor vehicle accident: Case report

Abstract

We examined the endocrine profile of a boy aged 10 years and 4 months with intracranial hypotension syndrome (IHS) following a motor vehicle accident. His complaint was growth disturbance. GH secretion gradually decreased and finally was lost in spite of an epidural blood patch procedure. His height velocity was restored by GH replacement therapy. MRI and SPECT revealed damage to the hypothalamic and pituitary gland. We concluded that growth disturbance is an important sign in pediatric patients with hypothalamic damage associated with IHS.