In-vivo dark-field and phase-contrast x-ray imaging

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Abstract

Novel radiography approaches based on the wave nature of x-rays when propagating through matter have a great potential for improved future x-ray diagnostics in the clinics. Here, we present a significant milestone in this imaging method: in-vivo multi-contrast x-ray imaging of a mouse using a compact scanner. Of particular interest is the enhanced contrast in regions related to the respiratory system, indicating a possible application in diagnosis of lung diseases (e.g. emphysema).

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Bech, M., Tapfer, A., Velroyen, A., Yaroshenko, A., Pauwels, B., Hostens, J., … Pfeiffer, F. (2013). In-vivo dark-field and phase-contrast x-ray imaging. Scientific Reports, 3. https://doi.org/10.1038/srep03209

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