CH…π Interaction in Organic Molecules

Abstract

CH…π interaction, which is one of weak non-covalent hydrogen bonds (H-bonds), plays an important role in physics, chemistry, and biology. First, definition of the H-bond is introduced, and a position of the CH…π H-bond is confirmed. Next, several experimental evidence of the CH…π H-bond are described. Then, consequence of the CH…π H-bond in organic chemistry such as conformation, reaction selectivity, and molecular recognition is discussed especially from recent results.