A case of hereditary angioedema involving recurrent abdominal attacks

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Abstract

A 44-year-old Japanese woman was diagnosed with type 1 hereditary angioedema (HAE) at the age of 30. In March 2007, she began suffering from severe abdominal pain due to intestinal edema. After treatment with C1-INH concentrate, her symptoms disappeared. However, during the subsequent three years, the frequency of the attacks increased continuously, and C1-INH concentrate was necessary for treatment of every attack. The increase in the number of attacks might have been due to the frequent injection of C1-INH concentrate or the deterioration of her disease course. In a genetic investigation, the patient was found to have a novel mutation in the C1-INH gene. © 2011 The Japanese Society of Internal Medicine.

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Kasamatsu, Y., Yoshinoya, K., Kasamatsu, Y., Yamamoto, T., Horiuchi, T., & Kadoya, M. (2011). A case of hereditary angioedema involving recurrent abdominal attacks. Internal Medicine, 50(23), 2911–2914. https://doi.org/10.2169/internalmedicine.50.6224

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