Photosensitivity in the elderly - Think of late-onset protoporphyria

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Abstract

Photosensitivity is the clinical hallmark of both erythropoietic protoporphyria (EPP) and X-linked dominant protoporphyria (XLDPP). Both disorders result from a hereditary dysfunction in heme biosynthesis. Disease onset is usually in early childhood. However, rare patients with late-onset EPP in association with a myeloproliferative disorder or myelodysplastic syndrome have been reported. In this issue, Livideanu et al. describe the first patient with late-onset XLDPP.

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Frank, J., Poblete-Gutiérrez, P., & Neumann, N. J. (2013). Photosensitivity in the elderly - Think of late-onset protoporphyria. Journal of Investigative Dermatology. Nature Publishing Group. https://doi.org/10.1038/jid.2013.80

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