Layer separation for vessel enhancement in interventional X-ray angiograms using morphological filtering and robust PCA

Abstract

Automatic vessel extraction from X-ray angiograms (XA) for percutaneous coronary interventions is often hampered by low contrast and presence of background structures, e.g. diaphragm, guiding catheters, stitches. In this paper, we present a novel layer separation technique for vessel enhancement in XA to address this problem. The method uses morphological filtering and Robust PCA to separate interventional XA images into three layers, i.e. a large-scale breathing structure layer, a quasi-static background layer and a layer containing the vessel structures that could potentially improve the quality of vessel extraction from XA. The method is evaluated on several clinical XA sequences. The result shows that the proposed method significantly increases the visibility of vessels in XA and outperforms other background-removal methods.