Gastric IgG4-Related Autoimmune Fibrosclerosing Pseudotumour: A Novel Location

  • Rollins K
  • Mehta S
  • O'Donovan M
  • et al.
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Abstract

We describe the first reported case of an IgG4-related autoimmune fibrosclerosing pseudotumour located in the stomach of a 75-year old woman presenting with weight loss and vomiting. A lesion was detected in the gastric body at endoscopy. Subsequent characterisation by CT was suggestive of a gastrointestinal stromal tumour. Following laparoscopic resection, the patient recovered uneventfully. Histological examination of the resected specimen revealed an IgG4-related fibrosclerosing pseudotumour, a novel location for this histopathological entity.

Figures

  • Figure 1: Oesophagogastroduodenoscopy (OGD). The large polypoid mass seen in gastric midbody.
  • Figure 3: Histopathological analysis at 40x. Haematoxylin and eosin stain showing plump spindle cells set in a fibrous stroma with eosinophilic material and admixed inflammatory cells.
  • Figure 2: Computed tomography scan. Gastric mass arising from medial wall of stomach.
  • Figure 4: Histopathological analysis at 40x. IgG4 immunohistochemistry demonstrating IgG4 positive plasma cells.

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APA

Rollins, K. E., Mehta, S. P., O’Donovan, M., & Safranek, P. M. (2011). Gastric IgG4-Related Autoimmune Fibrosclerosing Pseudotumour: A Novel Location. ISRN Gastroenterology, 2011, 1–3. https://doi.org/10.5402/2011/873087

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