An enzymatic methodology for the preparation of β-hydroxy-α- amino acid derivatives is described. The method consists of the stereoselective aldol addition reaction of glycine to N-Cbz-amino aldehydes furnishing 3-hydroxy-2,4-diaminobutyric derivatives.
CITATION STYLE
Clapés, P., Joglar, J., & Gutiérrez, M. (2012). Carbon-carbon bond-forming enzymes for the synthesis of non-natural amino acids. Methods in Molecular Biology, 794, 73–85. https://doi.org/10.1007/978-1-61779-331-8_5
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