Regulatory Oversight and Safety Assessment of Flavorings

Abstract

This chapter serves as an example of governmental regulatory oversight and safety assessment of flavorings. In the European Union (EU), the regulatory framework for the use of flavorings flavoring in and on foods is provided by Regulation (EC) No 1334/2008. The Regulation provides for three basic regulatory tools: (i) a Union list of flavorings and source materials approved for use in and on foods, (ii) conditions of use of flavorings and food ingredients with flavoring properties in and on foods, and (iii) rules on the labeling of flavorings. The safety evaluation of flavoring flavoringsafety evaluation substances has been performed using a group-based approach. The procedure is based on a decision tree that considers information on structure–activity relationships, metabolism, intake, and toxicity.