Biotechnology and bioinformatics applications in alzheimer’s disease

Abstract

Alzheimer’s disease is one of the most severe types of dementia that causes problems with memory, thinking, and behavior. Biotechnology and bioinformatics are nowadays involved in the establishment of advanced methods of diagnosis and treatment, including molecular medicine, personalized medicine, gene identification and manipulation, as well as neural engineering. Next-generation sequencing is one of the strongest tools for studying genetic diseases and gene mutations. Additionally, brain-computer interface could be used in the near future to assist people with paralysis or other related disorders and physical injuries to move toward into a better way of life, restoring memory or improving the way of everyday life. This chapter aims to provide an overview of the most common and an advanced application of biotechnology and bioinformatics in Alzheimer’s including the genome-wide association studies and the role of microbiome detection in Alzheimer’s disease.