Necroptosis in macrophages is increasingly being recognized as a significant contributor to the inflammation seen in many pathologies. Here we describe a well-known method to obtain quiescent, mature macrophages that can be used to study the molecular mechanisms that regulate necroptosis. We also describe two ways to quantify this form of programmed cell death.
CITATION STYLE
Legarda, D., & Ting, A. T. (2018). Analysis of necroptosis in bone marrow-derived macrophages. In Methods in Molecular Biology (Vol. 1857, pp. 63–70). Humana Press Inc. https://doi.org/10.1007/978-1-4939-8754-2_6
Mendeley helps you to discover research relevant for your work.