The role of physiotherapy in Marfan syndrome

Abstract

Marfan syndrome is frequently associated with a variety of musculoskeletal abnormalities which have the potential to produce symptoms throughout life. Joint hypermobility is one of the most common musculoskeletal features, affecting 85 % of children and 56 % of adults [1]. Hypermobility caused by ligamentous laxity can lead to poor joint control, rendering the individual prone to pain, recurrent joint sprains and strains, including subluxation and dislocation. The finger, ankle and patellofemoral joints are affected most frequently in the Marfan population. In a small percentage this can progress to early onset osteoarthritis. Scoliosis is also common, being present in 60 % of individuals with Marfan syndrome [2]. This can lead to progressive deformity, particularly during the growth spurts and be associated with back pain and restricted ventilatory capacity.