Inaugural Charles River World Congress on Animal Models in Drug Discovery and Development

Abstract

The proceedings contain 15 papers. The topics discussed include: bench to bedside in oncology: translation of cancer vaccines from mouse models to human clinical trials; rat models of susceptibility to complex diseases: a solution to Eroom's law; diet preferences in large animal models of cardiovascular disease: does it matter?; rapid 3D bioprinting of blood vessel network and microphysiological systems; the translational medicine guide: asking the right question at the right time; development of human antibodies for the treatment of protein aggregation diseases; exercise capacity, aging, and longevity; a unifying model to explain primary and compensatory immune resilience of cancer; and understanding complex interactions in metabolic and cardiovascular disease: genetics, the microbiome, sex, and diet.