Pemphigus Foliaceus and Endemic Forms

Abstract

Autoimmune bullous diseases are a heterogeneous group of diseases also in terms of epidemiological characteristics. Recent high-quality epidemiological studies have provided valuable new knowledge in this area. It has become clear that the incidence of bullous pemphigoid in Central Europe has at least doubled over the last decade and that incidences of the different autoimmune diseases vary considerably between geographical regions. The increased mortality risk as well as the association with neurological diseases in patients with bullous pemphigoid has been highlighted in several studies, raising the intriguing question about the link between the neurological and skin diseases in affected patients.