Efinaconazole 10% topical solution is a new triazole recently approved for the treatment of onychomycosis. It inhibits fungal lanosterol 14-demethylase in the ergosterol biosynthesis pathway, has potent antifungal activity against dermatophytes, as well as activity against Candida spp. and non-dermatophyte molds, and showed promising results in clinical trials. This review summarizes the mechanism of action, in vitro and in vivo data, clinical trials, safety, and quality-of-life data of efinaconazole as it applies to the treatment of onychomycosis
CITATION STYLE
Lipner, S. R., & Scher, R. K. (2015). Efinaconazole in the treatment of onychomycosis. Infection and Drug Resistance, 8, 163–172. https://doi.org/10.2147/IDR.S69596
Mendeley helps you to discover research relevant for your work.