Objective: To evaluate the efficacy and safety of adalimumab in the management of ocular inflammation at our institution. Methods: We performed a review of all patients with active ocular inflammation treated with adalimumab at our institution. Results: Seventy eyes of 49 patients were reviewed. The mean duration of follow-up was 19.6 months. Therapy with an average of 2.1 immunomodulatory agents had been attempted prior to adalimumab therapy. At 1-year follow-up, adalimumab was effective in achieving quiescence in 33 eyes (47%). The most common side effects were injection-site reactions, arthralgias, and nausea, occurring in two patients each. Adalimumab was discontinued due to side effects in 12 patients. Conclusion: These results suggest that adalimumab is an effective and safe therapeutic modality in ocular inflammation.
CITATION STYLE
Arcinue, C. A., Durrani, K., Artornsombudh, P., Radwan, A., Parikh, R., Suelves, A. M., … Foster, C. S. (2015). The efficacy and safety of adalimumab in ocular inflammatory disease. Orphan Drugs: Research and Reviews, 5, 69–74. https://doi.org/10.2147/ODRR.S69582
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