Abstract
Streptococcal agent OK‐432 was administered at maintenance levels with conventional inductive chemotherapeutic agents to stage III and IV lung cancer patients. Survival rates were longer in patients treated with OK‐432 than in patients treated without OK‐432. An enhancement of lymphocyte blastogenic activity and a delayed PPD skin reaction were found in patients treated by OK‐432. A low grade fever was present as a side effect of this agent in some patients. The results suggest that OK‐432 may be a useful immunotherapeutic agent in combination with induction chemotherapy in reducing host damage in advanced stages of lung cancer. Copyright © 1976 American Cancer Society
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CITATION STYLE
Kimura, I., Ohnoshi, T., Yasuhara, S., Sugiyama, M., Urabe, Y., Fujii, M., & Machida, K. ‐I. (1976). Immunochemotherapy in human lung cancer using the streptococcal agent OK‐432. Cancer, 37(5), 2201–2203. https://doi.org/10.1002/1097-0142(197605)37:5<2201::AID-CNCR2820370507>3.0.CO;2-Q
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