Photophysical and in vitro antibacterial studies of 2,6-dibromo-BODIPY dye substituted with dithienylenevinylene at 3,5-positions

Abstract

Photophysical properties of synthesized 2,6-brominated BODIPY dyes having dithienylenevinylene at 3,5-positions have been investigated in different solvents combining experiment and time dependent density functional theory (TDCAM- B3LYP). This study shows a good agreement between the measured and computed excitation energies with a small deviation of 25-40 nm. The UV-Visible range corresponding to the electronic transition involving HOMO, HOMO- 1 and LUMO orbitals is also reported. Further, the assessment of the antimicrobial activity of the 2,6-brominated BODIPY and 2,6-brominated BODIPY substituted with distyryl at 3,5-postions has shown that at lower concentrations (3.12·10-3 mg/mL) these synthesized compounds are able to eradicate E. coli and S. aureus upon 25 minutes irradiation using LEDs shining light at 530 nm and 650 nm.