Glucose and lipid profile together with blood pressure should always be considered for low sera-IGF-1 patients. Even when adulthood is reached, IGF-1 therapy in these patients should be pursued as metabolic and protective cellular effects could be triggered. Real incidence of growth hormone insensitivity is still to be uncovered.
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Castilla-Cortazar, I., Femat-Roldán, G., Rodríguez-Rivera, J., Aguirre, G. A., García-Magariño, M., Martín-Estal, I., … Díaz-Olachea, C. (2017). Mexican case report of a never-treated Laron syndrome patient evolving to metabolic syndrome, type 2 diabetes, and stroke. Clinical Case Reports, 5(11), 1852–1855. https://doi.org/10.1002/ccr3.1193
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