Role of neurogenomics in the development of personalized neurology

Abstract

Personalized medicine is defined by the author as an integration of various biotechnologies to provide treatment best suited for a patient taking into consideration genomic as well as non-genomic factors. This chapter focuses on the role of neurogenomics in the development of personalized neurology, and the relationship to other relevant "omics" such as neuroproteomics is pointed out. Several of the genes relevant to neurological disorders have been sequenced, and their relation to various neurological disorders is under investigations. Genomic technologies may play a role in molecular diagnostics, biomarkers, as well as treatment of neurological disorders. The role of pharmacogenomics and pharmacogenetics in pharmacotherapy of various diseases is also discussed.