Depression in Japanese patients with chronic obstructive pulmonary disease: A cross-sectional study

Abstract

Some investigations have revealed an association between depression and physical measurements of COPD patients in North America and Europe, but few related studies have been performed in Asia. METHODS: In this cross-sectional study, 84 consecutive, stable outpatients with COPD (mean ±SD age 72.±0 9.0 y, percent-of-predicted FEV1 46 15%, 15 [17.9%] female) in a Japanese community hospital were recruited. "Probable depression" was defined as a score of > 6 on the short-form Geriatric Depression Scale (SF-GDS). Relationships among commonly used physical measurements, SF-GDS raw score, and probable depression were evaluated with the Spearman rank correlation test, multiple linear regression analysis, logistic regression analysis, and receiver operating characteristic curves. RESULTS: Thirty-two subjects (38.1%) had probable depression. Body mass index, obstruction, dyspnea, exercise capacity index, percent-of-predicted FEV1 Modified Medical Research Council dyspnea score, 6-min walk distance, and SpO2 had: simple correlations (r 0.42 - 0.60, P