The renin angiotensin system (RAS) is an established regulator of intravascular volume and arterial pressure. It is now clear that complete and partial RASs exist in multiple tissues, including the cardiovascular system, with the result that local regulation of angiotensin can occur. In addition, newly identified factors such as ACE 2 and the (pro)renin receptor expand the potential physiological actions of these tissue RASs. Here evidence for the existence and functional relevance of local RASs in cardiovascular tissues is reviewed.
CITATION STYLE
Re, R. N. (2009). Local Renin Angiotensin Systems in the Cardiovascular System. In Renin Angiotensin System and Cardiovascular Disease (pp. 25–34). Humana Press. https://doi.org/10.1007/978-1-60761-186-8_4
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