A Survey of Computational Methods for Determining Haplotypes

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Abstract

It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (SNPs) are the most common form of genomic variation. Haplotypes have been suggested as one means for reducing the complexity of studying SNPs. In this paper we review some of the computational approaches that have been taking for determining haplotypes and suggest new approaches. © Springer-Verlag 2004.

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Halldórsson, B. V., Bafna, V., Edwards, N., Lippert, R., Yooseph, S., & Istrail, S. (2004). A Survey of Computational Methods for Determining Haplotypes. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2983, 26–47. https://doi.org/10.1007/978-3-540-24719-7_3

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