Acne vaccines: Therapeutic option for the treatment of acne vulgaris?

Abstract

Acne, one of the most common skin diseases, is caused by multiple factors, including Propionibacterium acnes. Studies suggest that responses to P. acnes by host immunity play important roles in its pathogenesis. Identifying immune modulators that attenuate inflammatory responses against P. acnes and the inhibition of bacterial growth may lead to novel avenues of immunologic intervention. © 2008 The Society for Investigative Dermatology.