MRI bone segmentation using deformable models and shape priors

Abstract

This paper addresses the problem of automatically segmenting bone structures in low resolution clinical MRI datasets. The novel aspect of the proposed method is the combination of physically-based deformable models with shape priors. Models evolve under the influence of forces that exploit image information and prior knowledge on shape variations. The prior defines a Principal Component Analysis (PCA) of global shape variations and a Markov Random Field (MRF) of local deformations, imposing spatial restrictions in shapes evolution. For a better efficiency, various levels of details are considered and the differential equations system is solved by a fast implicit integration scheme. The result is an automatic multilevel segmentation procedure effective with low resolution images. Experiments on femur and hip bones segmentation from clinical MRI depict a promising approach (mean accuracy: 1.44 ± 1.1 mm, computation time: 2mn43s). © 2008 Springer-Verlag Berlin Heidelberg.