In this issue of Cell Metabolism, Thomas et al. (2009) show that specific activation of the bile-acid-activated G protein-coupled receptor TGR5 improves pancreatic and hepatic function and impairs the development of obesity following administration of a high-fat diet. © 2009 Elsevier Inc. All rights reserved.
Vallim, T. Q. de A., & Edwards, P. A. (2009, September 2). Bile Acids Have the Gall to Function as Hormones. Cell Metabolism. https://doi.org/10.1016/j.cmet.2009.08.005