Blood microRNAs in low or no risk ischemic stroke patients

Citations of this article
Mendeley users who have this article in their library.


Ischemic stroke is a multi-factorial disease where some patients present themselves with little or no risk factors. Blood microRNA expression profiles are becoming useful in the diagnosis and prognosis of human diseases. We therefore investigated the blood microRNA profiles in young stroke patients who presented with minimal or absence of risk factors for stroke such as type 2 diabetes, dyslipidemia and hypertension. Blood microRNA profiles from these patients varied with stroke subtypes as well as different functional outcomes (based on modified Rankin Score). These microRNAs have been shown to target genes that are involved in stroke pathogenesis. The findings from our study suggest that molecular mechanisms in stroke pathogenesis involving low or no risk ischemic stroke patients could differ substantially from those with pre-existing risk factors.




Tan, J. R., Tan, K. S., Koo, Y. X., Yong, F. L., Wang, C. W., Armugam, A., & Jeyaseelan, K. (2013). Blood microRNAs in low or no risk ischemic stroke patients. International Journal of Molecular Sciences, 14(1), 2072–2084.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free