In recent years, the response of, especially, the right ventricle to intense exercise has gained increased interest. In this study, we use the CircAdapt model to evaluate the influence of inter-individual variation of pulmonary vascular resistance during exercise on cardiovascular hemodynamics. We modeled pulmonary vascular resistance as a nonlinear resistive module in which the resistance increases proportionally to stroke volume. We modeled inter-individual variation following normal random distributions. To evaluate the hemodynamic response to exercise, we computed pulmonary artery systolic pressure and end-systolic wall stress. With our modeling strategy, we were able to reproduce the phenomena observed clinically. © 2013 Springer-Verlag.
CITATION STYLE
Tobon-Gomez, C., Palau-Caballero, G., Sitges, M., & Bijnens, B. H. (2013). Exercise induced inter-individual variation of right ventricular pressures: Simulations using a modular model of the cardiovascular system. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 7746 LNCS, pp. 336–344). https://doi.org/10.1007/978-3-642-36961-2_38
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