Two new Scalaranes from a Korean marine sponge Spongia sp

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Abstract

Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined based on the analysis of 1H-1H coupling constants and NOESY spectroscopic data. Compounds 1 and 2 did not display any significant biological activities on farnesoid X-activated receptor (FXR) in co-transfection assay.

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Yang, I., Nam, S. J., & Kang, H. (2015). Two new Scalaranes from a Korean marine sponge Spongia sp. Natural Product Sciences, 21(4), 289–292. https://doi.org/10.20307/nps.2015.21.4.289

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