Effect of Nucleotide on Growth, Immune Responses and Resistance of Labeo Rohita to Aeromonas Hydrophila Infection

Abstract

A 60-day feeding trial was conducted to evaluate the effect of dietary nucleotide on growth, survival, immunity and resistance to Aeromonas hydrophila infection in rohu (Labeo rohita). The nucleotide was supplemented at 0, 5, 10 and 15 g/kg diet. The test diets were fed for 60 days in triplicate groups of fish, which had initial weight of 1.3 g. At the end of the feeding trial, growth was recorded and non-specific immune parameters, such as; superoxide anion production and total serum protein were studied in blood samples. Total serum protein and superoxide anion production were significantly (P<0.05) higher in fish fed nucleotide-based diets. The relative percent survival of fish after the challenge test against Aeromonas hydrophila disease was significantly (P<0.05) higher in fish fed nucleotide-incorporated diets.