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Characterization of Plasmodium vivax heat shock protein 70 and evaluation of its value for serodiagnosis of tertian malaria

Clinical and Vaccine Immunology (2007) 14(3) 320-322
DOI: 10.1128/CVI.00424-06
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Abstract

We have characterized Plasmodium vivax heat shock protein 70 (PvHSP70) and evaluated serodiagnostic applicability of recombinant PvHSP70 (rPvHSP70). In enzyme-linked immunosorbent assays and immunoblot analyses, rPvHSP70 showed high sensitivity (88.8%; 203/228 cases). P. falciparum-infected sera revealed positive reactions (78.8%). The predominant immunoglobulin G (IgG) subclasses were segregated with IgG1 and IgG3. Copyright © 2007, American Society for Microbiology. All Rights Reserved.

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Na, B. K., Park, J. W., Lee, H. W., Lin, K., Kim, S. H., Bae, Y. A., … Kong, Y. (2007). Characterization of Plasmodium vivax heat shock protein 70 and evaluation of its value for serodiagnosis of tertian malaria. Clinical and Vaccine Immunology, 14(3), 320–322. https://doi.org/10.1128/CVI.00424-06

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