Czasteczki mikroRNA jako istotny skladnik mechanizmów regulacji ekspresji genów zwiazanych z nowotworami

Abstract

This paper presents the relationship between changes in the expression of specific microRNAs and the formation and development of selected cancers. An overview of reportsis provided on the usefulness of research on microRNA expression, which in the future may become valuable and desirable prognostic and prediction factors for diagnosticians and clinicians. miRNA will presumably become the cornerstone for the development of new therapeutic approaches using antisense miRNAs (antagomirs) or drugs aimed at miRNA offsetting in the case of deletion or damage to their genes. It would offer the potential possibility of the regulation of gene expression which is of great significance for the origin and development of cancers. © Polskie Towarzystwo Onkologiczne ISSN 0029-540X.