Inflammatory diseases

Abstract

Inflammation is normally a localized, protective host response to trauma or infectious agents. Acute inflammation confines the area of injury, destroys or dilutes the injurious agent, and contributes to the restoration of tissue integrity [1]. Chronic inflammation, resulting from repeated exposure, persistent injury, or a failure to appropriately terminate the immune or inflammatory response, may lead to organ injury and morbidity. Current therapeutic strategies aim to suppress or redirect aberrant cellular responses to environmental and infectious stimuli.