DIABETIC EFFECTS OF POLYHERBAL FORMULATION OF LAWSONIA INERMIS AND AZADIRACHTA INDICA

  • Rajwar S
  • Khatri P
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Abstract

This Study was planned to investigate the different concentrate gradient formulation of Lawsonia inermis and Azadirachta indica in Naproxen & Histamine induced model. In Naproxen induced model the test formulation of Azadirachta indica & Lawsonia inermis (F1) was significant and reduced the ulcer area to 2.4±0.12 mm 2 which is very near to standard. The test drug in F2 potency also significantly reduced the total ulcer area upto 3.58±0.11 mm 2. The test formulation was found insignificant in F3 and F4. But Formulation F5 had extraverted the ulcer area upto an great extent to 30.41±0.21 mm 2 and is completely insignificant. In Histamine induced ulcer model states that the total ulcerative area in control (no drug) group was 10.65±0.06 mm 2 whereas in standard (Ranitidine) group it significantly reduced to 2.71±0.12 mm 2. The test formulation of Azadirachta indica & Lawsonia inermis F1, F2 and F3 were significant and reduced the ulcer area to 8.1±0.12mm 2 and 8.86±0.13 mm 2. Whearas F4 was non significant. But F5 had extraverted the ulcer area upto an great extent to 63.56±0.24 mm 2 and is completely insignificant.

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Rajwar, S., & Khatri, P. (2013). DIABETIC EFFECTS OF POLYHERBAL FORMULATION OF LAWSONIA INERMIS AND AZADIRACHTA INDICA. Journal of Drug Delivery and Therapeutics, 3(2). https://doi.org/10.22270/jddt.v3i2.415

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