Abstract
Two venlafaxine (Effexor)-related deaths are reported with comparison of results from the analysis of specimens using capillary gas chromatography with a nitrogen-phosphorous detector (GC-NPD) and high-performance liquid chromatography (HPLC) using a UV-vis detector. Blood concentrations in Case 1 were 7.27 μg/mL venlafaxine and 5.03 μg/mL O-desmethylvenlafaxine, and Case 2 had 89.67 μg/mL venlafaxine with 3.44 μg/mL of the desmethyl metabolite. A comparison of analytical methods and specimen concentration is presented.
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CITATION STYLE
Long, C., Crifasi, J., Maginn, D., Graham, M., & Teas, S. (1997). Comparison of analytical methods in the determination of two venlafaxine fatalities. Journal of Analytical Toxicology, 21(2), 166–169. https://doi.org/10.1093/jat/21.2.166
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