Convenient Synthesis of Glycan-Related Oligosaccharides and Their Transformation into Neoglycoconjugates Using Enzymatic Methods

Abstract

Glycan-related oligosaccharides involved in a number of biological events. However, there is a paucity of structurally defined oligosaccharides that have been isolated from biological material. Currently, there is a great interest in developing synthetic routes for the oligosaccharide portion of glycoconjugates. The development of simple and effective methods for synthesizing neoglycoconjugates as mimetics of glycoproteins and glycolipids is also essential for the understanding of the biological function of these molecules. Here, we review the recent developments in the synthesis of glycan-related oligosaccharides and neoglycoconjugates.