DNA secondary structure forming at minisatellite repeat unit sequences.

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Abstract

The lengths of simple repeat sequences are generally unstable or polymorphic; that is, they are highly variable with respect to the numbers of tandem repeats. To determine the structural features that cause such variability, we examined a minisatellite DNA isolated from the yellow fin sea bream Acanthopagrus latus. Electrophoresis, CD spectra, and calorimetric analyses of oligodeoxyribonucleotides comprised of the minisatellite repeat unit suggest a stable secondary structure is formed within the repeat unit.

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Haku, T., Hibino, T., Fukada, H., Mishima, Y., Yamashita, I., & Kato, M. (2006). DNA secondary structure forming at minisatellite repeat unit sequences. Nucleic Acids Symposium Series (2004), (50), 229–230. https://doi.org/10.1093/nass/nrl114

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