Mechanical and Morphological Characterization of Chitosan Scaffolds Produced by Particle Aggregation Method

Abstract

Development of novel biomaterials and its practical application have been the subject of much research in the field of scaffolds for tissue engineering, providing the success of producing scaffolds biomaterials that facilitate tissue growth and provide structure support for cells. The design and production of scaffolds for tissue engineering is yet unable to completely reproduce the native tissue properties. Preferably, scaffolds would be made of biodegradable polymers whose properties are more similar to the ECM. Chitosan, which is the copolymer of D-glucosamine and N-acetyl-D-glucosamine, is an excellent material due to its versatile properties and is one of the widely studied polymers for tissue engineering application. The objective of the present work was to characterize mechanical and morphological chitosan scaffolds pro- duced by a particle aggregation method...