The Impact and Management of Gynaecomastia in Klinefelter Syndrome

Abstract

Gynecomastia is defined as a palpable enlargement of the male breast, secondary to anincrease in the glandular and stromal breast tissue. Gynecomastia is encountered in up to80% of Klinefelter syndrome cases. The pathophysiology involves testosterone/estrogenimbalance. This review article will further explore the pathophysiology of gynecomastiaalong with the different lines of management.