Abstract
This case discusses the pharmacokinetic interaction of caffeine, ethinylestradiol, and ciprofloxacin, resulting in caffeine toxicity Caffeine is a cytochrome P450 1A2 substrate. Both ciprofloxacin and ethinylestradiol inhibit 1A2. The physiologic effects of ingestion of high doses of caffeine are also reviewed.
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CITATION STYLE
APA
Gierl, B., & Romeo, R. (2015). Caffeine crash: Fatal forty DDI: Caffeine, ethinylestradiol, ciprofloxacin, CYP1A2. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 917–920). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_206
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