Toward personalized therapy in inflammatory bowel disease

Abstract

Inflammatory bowel disease (IBD) is a heterogeneous disease with patients experiencing varying disease courses and response to therapy. Developing precision medicine approaches is of great interest and importance to improve care for IBD patients. Recent advances have the potential to change the way clinicians stratify patients and then select the most appropriate treatment based on an individualized assessment of risk of complications and drug response. In this chapter, we provide concluding remarks on the current evidence and potential for genomics in IBD care and future directions to bring precision medicine approaches to the clinic.