Introduction: Asthma poses a significant burden for the Australian population. Understanding severe exacerbation rates, and steroidrelated burden for adults diagnosed with asthma stands to offer insights into how this could be reduced. Methods: Electronic medical records (EMR) and questionnaires from the Optimum Patient Care Research Database Australia (OPCRDA) were utilised retrospectively. OPCRDA is a real-world database with >800,000 medical records from Australian primary care practices. Outcomes were severe asthma exacerbations in Australian adults, over a 12-month period, stratified by Global Initiative for Asthma (GINA) treatment intensity steps, and steroid associated comorbidities. Results: Of the 7868 adults treated for asthma, 19% experienced at least one severe exacerbation in the last 12-months. Severe exacerbation frequency increased with treatment intensity (>= 1 severe exacerbation GINA 1 13%; GINA 4 23%; GINA 5a 33% and GINA 5b 28%). Questionnaire participants reported higher rates of severe exacerbations than suggested from their EMR (32% vs specialist assessment to better manage their condition.
CITATION STYLE
Hancock, K. L., Bosnic-Anticevich, S., Blakey, J. D., Hew, M., Chung, L. P., Cvetkovski, B., … Price, D. (2022). Characterisation of the Australian Adult Population Living with Asthma: Severe - Exacerbation Frequency, Long-Term OCS Use and Adverse Effects. Pragmatic and Observational Research, Volume 13, 43–58. https://doi.org/10.2147/por.s360044
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