P16 immunohistochemical expression, a surrogate marker of the retinoblastoma pathway, has become a major adjunct in the routine practice mostly of cervical and head/neck pathology, but with other indications too. In this chapter, a detailed immunohistochemical technique for the detection of p16 is described, followed by indications and interpretation of its expression in uterine, ovarian, vulvar, penile, head-and-neck, melanocytic, and other pathologies.
CITATION STYLE
Karpathiou, G., & Peoc’h, M. (2018). Immunohistochemical detection of p16 in clinical samples. In Methods in Molecular Biology (Vol. 1726, pp. 123–142). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7565-5_12
Mendeley helps you to discover research relevant for your work.