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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

Nature Communications (2019) 10(1)
DOI: 10.1038/s41467-019-13471-0
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Abstract

70% of HNSCC lesions respond to intratumoral anti-CTLA-4. This syngeneic HNSCC mouse model provides a platform to accelerate the development of immunotherapeutic options for HNSCC.

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Wang, Z., Wu, V. H., Allevato, M. M., Gilardi, M., He, Y., Luis Callejas-Valera, J., … Gutkind, J. S. (2019). Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4. Nature Communications, 10(1). https://doi.org/10.1038/s41467-019-13471-0

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