Background: Despite the wealth of information carried, periodic brain monitoring data are often incomplete with a significant amount of missing values. Incomplete monitoring data are usually discarded to ensure purity of data. However, this approach leads to the loss of statistical power, potentially biased study and a great waste of resources. Thus, we propose to reuse incomplete brain monitoring data by imputing the missing values-a green solution! To support our proposal, we have conducted a feasibility study to investigate the reusability of incomplete brain monitoring data based on the estimated imputation error. Materials and Methods: Seventy-seven patients, who underwent invasive monitoring of ICP, MAP, PbtO 2 and brain temperature (BTemp) for more than 24 consecutive hours and were connected to a bedside computerized system, were selected for the study. In the feasibility study, the imputation error is experimentally assessed with simulated missing values and 17 state-of-the-art predictive methods. A framework is developed for neuroclinicians and neurosurgeons to determine the best re-usage strategy and predictive methods based on our feasibility study. Results/Conclusion: The monitoring data of MAP and BTemp are more reliable for reuse than ICP and PbtO 2; and, for ICP and PbtO 2 data, a more cautious re-usage strategy should be employed. We also observe that, for the scenarios tested, the lazy learning method, K-STAR, and the tree-based method, M5P, are consistently 2 of the best among the 17 predictive methods investigated in this study. © 2012 Springer-Verlag/Wien.
CITATION STYLE
Feng, M., Loy, L. Y., Zhang, F., Zhang, Z., Vellaisamy, K., Chin, P. L., … Ang, B. T. (2012). Go green! Reusing brain monitoring data containing missing values: A feasibility study with traumatic brain injury patients. In Acta Neurochirurgica, Supplementum (Vol. 114, pp. 51–59). Springer-Verlag Wien. https://doi.org/10.1007/978-3-7091-0956-4_10
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