Synthesis and absolute configuration of MQ-A3 [1-(14′-methylhexadecanoyl) pyrrolidine], a novel aliphatic pyrrolidine amide from the tropical convolvulaceous species

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Abstract

A novel pyrrolidine amide (MQ-A3) isolated from the tropical convolvulaceous species was synthesized in 5 steps by starting from commercially available 12-bromododecanol and (S)-2-methylbulylbromide. The absolute configuration of the natural product was confirmed by a comparison of the specific rotation values.

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Yajima, A., & Yabuta, G. (2001). Synthesis and absolute configuration of MQ-A3 [1-(14′-methylhexadecanoyl) pyrrolidine], a novel aliphatic pyrrolidine amide from the tropical convolvulaceous species. Bioscience, Biotechnology and Biochemistry, 65(2), 463–465. https://doi.org/10.1271/bbb.65.463

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