Agarofuran-, Eudesmane- and Eremophilane-Type Sesquiterpenoids from Alpinia japonica (THUNB.) MIQ

Abstract

Three new sesquiterpenoids, 3α,4α-oxidoagarofuran, 3β,4β-oxidoagarofuran and Δ9(10)-eremophilen-ll-ol, as well as 10-epi-γ-eudesmol, 4α-hydroxydihydroagarofuran, α-agarofuran, dihydroagarofuran and β-Teudesmol were isolated from the rhizome of Alpinia japonica. Their structures were determined by chemical and spectroscopic methods. It is interesting from a biogenetic point of view that Δ9(10)-eremophilen-ll-ol, β-eudesmol and agarofurans which possess the 10-epimeric eudesmane carbon skeleton were all contained in the same plant. © 1985, The Pharmaceutical Society of Japan. All rights reserved.