PHIST: Fast and accurate prediction of prokaryotic hosts from metagenomic viral sequences

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Abstract

Summary: Phage-Host Interaction Search Tool (PHIST) predicts prokaryotic hosts of viruses based on exact matches between viral and host genomes. It improves host prediction accuracy at species level over current alignment-based tools (on average by 3 percentage points) as well as alignment-free and CRISPR-based tools (by 14-20 percentage points). PHIST is also two orders of magnitude faster than alignment-based tools making it suitable for metagenomics studies.

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APA

Zielezinski, A., Deorowicz, S., & Gudyś, A. (2022). PHIST: Fast and accurate prediction of prokaryotic hosts from metagenomic viral sequences. Bioinformatics, 38(5), 1447–1449. https://doi.org/10.1093/bioinformatics/btab837

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