Biosensors, the Emerging Tools in the Identification and Detection of Cancer Markers

Abstract

The cancer is chaos, causing impairment by biochemical pathways in a biological system. Mulfunctioning of cells throughout the human body is mostly observed in cancer and is still the outmost lethal disease in the world. There is a difference in expression of parameters within a host during its normal physiology and pathological conditions, those are identified and detected to proceed on for the treatment. A number of conventional methods are available nowadays, despite of their potential limitations. Biosensors, the analytical devices that convert biological responses into electrical signals are now popularly used in many fields such as food industry, metabolic engineering, plant biology, marine science, defense, drug discovery and development. Beside these, in the medical sectors, their important roles are remarkable, especially in the early detection of a disease, and monitoring the therapeutic progression and disease state. To date, diagnostic tests by using biosensors for the early detection of cancer biomarkers are available; these provide noninvasive/minimally invasive assays with high through output and patient survival rate. This paper reviews an overview on biosensor-implementation in some cancers along with their future applicability.