End-tidal, transcutaneous, and arterial PCO2 measurements in critically ill neonates: A comparative study

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Abstract

Non-invasive estimates of arterial CO2 (Pa(CO)2), such as end-tidal (PetCO2) and transcutaneous CO2 (PtcCO2), are alternatives to frequent arterial sampling. However, the accuracy of PetCO2 measurements in neonates has been questioned. Badgwell et al. determined the accuracy of PetCO2 measurements in healthy infants (≤ 12 kg in weight), and found that, with an aspirating capnometer, PetCO2 is significantly more accurate when gas is sampled from the distal end of the endotracheal tube rather than the proximal end. We speculated that distal PetCO2 measurements might also improve the accuracy of end-tidal estimates of PaCO2 in preterm and full-term neonates. Therefore, we compared the accuracy of PetCO2 and PtcCO2 measurements as estimates of PaCO2 in neonates.

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McEvedy, B. A. B., McLeod, M. E., Mulera, M., Kirpalani, H., & Lerman, J. (1988). End-tidal, transcutaneous, and arterial PCO2 measurements in critically ill neonates: A comparative study. Anesthesiology, 69(1), 112–116. https://doi.org/10.1097/00000542-198807000-00020

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